After a period of inactivity, interest in explanationism as a thesis about the nature of epistemic justification has been renewed. Poston and McCain have both recently offered versions of explanationist evidentialism. In this paper, we pose two objections to explanationist evidentialism. First, explanationist evidentialism fails to state a sufficient condition for justification. Second, explanationist evidentialism implies a vicious regress.

This book offers a comprehensive critical survey of issues of historical interpretation and evaluation in Bertrand Russell's 1918 logical atomism lectures and logical atomism itself. These lectures record the culmination of Russell's thought in response to discussions with Wittgenstein on the nature of judgement and philosophy of logic and with Moore and other philosophical realists about epistemology and ontological atomism, and to Whitehead and Russell’s novel extension of revolutionary nineteenth-century work in mathematics and logic. Russell's logical atomism lectures have had (...) a lasting impact on analytic philosophy and on Russell's contemporaries including Carnap, Ramsey, Stebbing, and Wittgenstein. Comprised of 14 original essays, this book will demonstrate how the direct and indirect influence of these lectures thus runs deep and wide. (shrink)

Debate persists over the place of conscience in medicine. Some argue for the complete exclusion of conscientious objection, while others claim an absolute right of refusal. This paper proposes that claims of conscientious objection can and should be permitted if they concern kinds of actions which fall outside of the normative standard of medicine, which is the pursuit of health. Medical practice which meets this criterion we call medicine qua medicine. If conscientious refusal concerns something consonant with the health-restoring aims (...) of medicine, it entails a desertion of professional duty. If, however, it relates to something other than medicine qua medicine, it can rightly be refused. It thus becomes possible to test instances of conscientious objection to determine their validity, and thereby conserve both the principle of conscientious objection and define its scope. This test of conscience prevents arbitrary discrimination, and preserves doctors’ agency. It is a theoretical razor rooted in the pra... (shrink)

In _Civilization and Its Discontents_ Freud extends and clarifies his analysis of religion; analyzes human unhappiness in contemporary civilization; ratifies the critical importance of the death drive theory; and contemplates the significance of guilt and conscience in everyday life. The result is Freud’s most expansive work, one wherein he discusses mysticism, love, interpretation, narcissism, religion, happiness, technology, beauty, justice, work, the origin of civilization, phylogenetic development, Christianity, the Devil, communism, the sense of guilt, remorse, and ethics. A classic, important, accessible (...) work, Freud reminds us again why we still read and debate his ideas today. Todd Dufresne’s introduction expands on why, according to the late Freud, psychoanalysis is the key to understanding individual and collective realities or, better yet, collective truths. The Appendices include related writings by Freud, contemporary reviews, and scholarly responses from Marcuse, Rieff, and Ricoeur. (shrink)

Work-family conflict has been examined quite often in human resources management and industrial/organizational psychology literature. Numerous statistics show that the magnitude of this employment issue will continue to grow. As employees attempt to balance work demands and family responsibilities, organizations will have to decide to what extent they will go to minimize this conflict. Research has identified numerous negative consequences of work-family stressors for organizations, for employees and for employees' families. There are however many options to reduce this strain, each (...) with advantages and disadvantages. An ethical analysis, from a virtue ethics perspective, is applied to this timely issue to present an alternative view in addressing this critical business decision. In addition, a strong connection between the virtue ethics analysis and a well-known management theory is given to provide a foundation for managerial implications for resolving work-family conflict. (shrink)

This paper begins with a discussion of different definitions of “terrorism” and endorses one version of a tactical definition, so-called because it treats terrorism as involving the use of a quite specific tactic in the pursuit of political ends, namely, violent attacks upon the innocent. This contrasts with a political status definition in which “terrorism” is defined as any form of sub-state political violence against the state. Some consequences of the tactical definition are explored, notably the fact that it allows (...) for the possibility of state terrorism against individuals, sub-state groups and other states. But a major problem for the tactical definition is the account to be given of “the innocent.” In line with justwar thinking, the idea of “the innocent” is unpacked in terms of the concept of non-combatants and this in turn is treated as the category of those who are not prosecuting the harm that allows for a legitimate violent response. Problems with this approach are explored, with particular reference to criticisms made by Gregory Kavka. The recent drive to expand the class of those who may be legitimately attacked is subjected to scrutiny. Particular attention is paid to the role of “collective responsibility” and “deserving your government” in these arguments. (shrink)

This paper examines ways in which current moral values are influenced by earlier patterns of thinking carried forward in root metaphors whose meanings were often framed by the analogues settled upon in the past by thinkers who were influenced by the silences and prejudices of their culture. It is argued that such tacitly inherited metaphors reproduce the myth of the individual as a moral agent and that this both is ecologically unsustainable and undermines other important ways of understanding the individual. (...) In various ways the form of critical thinking to which it gives rise stands in the way of individuals exercising what Gregory Bateson refers to as their ?ecological intelligence? in a manner that properly takes account of the interdependent nature of cultural and natural ecologies. It is argued that if in the West (at least) a shift could be made to relying on ?ecology? as the dominant root metaphor the whole system of Western moral values would undergo a radical change to one better suited to a current Western environmental situation. (shrink)

Cas9/guide RNA (gRNA)‐based gene drive systems are expected to play a transformative role in malaria elimination efforts., whether through population modification, in which the drive system contains parasite‐refractory genes, or population suppression, in which the drive system induces a severe fitness load resulting in population decline or extinction. DNA sequence polymorphisms representing alternate alleles at gRNA target sites may confer a drive‐resistant phenotype in individuals carrying them. Modeling predicts that, for observed levels of SGV at potential target sites and observed (...) rates of de novo DRA formation, population modification strategies are uniquely resilient to DRAs. We conclude that gene drives can succeed when fitness costs incurred by drive‐carrying mosquitoes are low enough to prevent strong positive selection for DRAs produced de novo or as part of the SGV and that population modification strategies are less prone to failure due to drive resistance. (shrink)

A major aim of the books in this series is to promote psychology's appreciation of the neglected giants in its history. The chapters document the significance of these early contributions, many of them made more than a century ago. Most of the chapters are revisions of invited addresses delivered at psychological conventions. Several of the authors are students, colleagues, or offspring of their pioneers and all of them are intrigued by the life and work of the psychologists about whom they (...) have written. All of the portraits are informal; on occasion, even humorous. Some are "impersonations"--telling stories in what were or might have been the pioneer's own words. This book provides source materials for teachers of undergraduate courses in psychology--particularly the history of psychology--who want to add a personal view in their lectures and offer interesting readings for their students. Each of the five volumes in this series contains different profiles thereby bringing more than 100 of the pioneers in psychology more vividly to life. (shrink)

“Tell me," Wittgenstein once asked a friend, "why do people always say, it was natural for man to assume that the sun went round the earth rather than that the earth was rotating?" His friend replied, "Well, obviously because it just looks as though the Sun is going round the Earth." Wittgenstein replied, "Well, what would it have looked like if it had looked as though the Earth was rotating?” What would it have looked like if we looked at all (...) sciences from the viewpoint of Wittgenstein’s philosophy? Wittgenstein is undoubtedly one of the most influential philosophers of the twentieth century. His complex body of work has been analysed by numerous scholars, from mathematicians and physicists, to philosophers, linguists, and beyond. This volume brings together some of his central perspectives as applied to the modern sciences and studies the influence they may have on the thought processes underlying science and on the world view it engenders. The contributions stem from leading scholars in philosophy, mathematics, physics, economics, psychology and human sciences; all of them have written in an accessible style that demands little specialist knowledge, whilst clearly portraying and discussing the deep issues at hand. (shrink)

Previous long-term memory research found that angry faces were more poorly recognised when encoded with averted vs. direct gaze, while memory for happy faces was unaffected by gaze. Contrasti...

ABSTRACTFacial stimuli are widely used in behavioural and brain science research to investigate emotional facial processing. However, some studies have demonstrated that dynamic expressions elicit stronger emotional responses compared to static images. To address the need for more ecologically valid and powerful facial emotional stimuli, we created Dynamic FACES, a database of morphed videos from younger, middle-aged, and older adults displaying naturalistic emotional facial expressions. To assess adult age differences in emotion identification of dynamic stimuli and to provide normative ratings (...) for this modified set of stimuli, healthy adults categorised for each video the emotional expression displayed, rated the expression distinctiveness, estimated the age of the face model, and rated the naturalness of the expression. We found few age differences in emotion identification when using dynamic stimuli. On... (shrink)

We report the identification of a recurrent, 520-kb 16p12.1 microdeletion associated with childhood developmental delay. The microdeletion was detected in 20 of 11,873 cases compared with 2 of 8,540 controls and replicated in a second series of 22 of 9,254 cases compared with 6 of 6,299 controls. Most deletions were inherited, with carrier parents likely to manifest neuropsychiatric phenotypes compared to non-carrier parents. Probands were more likely to carry an additional large copy-number variant when compared to matched controls. The clinical (...) features of individuals with two mutations were distinct from and/or more severe than those of individuals carrying only the co-occurring mutation. Our data support a two-hit model in which the 16p12.1 microdeletion both predisposes to neuropsychiatric phenotypes as a single event and exacerbates neurodevelopmental phenotypes in association with other large deletions or duplications. Analysis of other microdeletions with variable expressivity indicates that this two-hit model might be more generally applicable to neuropsychiatric disease. © 2010 Nature America, Inc. All rights reserved. (shrink)

Mounting evidence shows that nature contact is associated with affective benefits. However, the psychological mechanisms responsible for these effects are not well understood. In this study, we examined whether more time spent in nature was associated with higher levels of positive affect in general, and lower levels of negative affect and rumination in general. We also conducted a cross-sectional mediation analysis to examine whether rumination mediated the association of nature contact with affect. Participants reported their average time spent in nature (...) each week, as well as their general levels of positive and negative affect, and the degree to which they typically engaged in rumination in daily life. We then used structural equation modeling to test our hypotheses. Our results support the hypothesis that nature contact is associated with general levels of affect, and that rumination mediates this association for negative affect, and marginally mediates this association for positive affect. (shrink)

Do the rich descriptions and narrative shapings of literature provide a valuable resource for readers, writers, philosophers, and everyday people to imagine and confront the ultimate questions of life? Do the human activities of storytelling and complex moral decision-making have a deep connection? What are the moral responsibilities of the artist, critic, and reader? What can religious perspectives—from Catholic to Protestant to Mormon—contribute to literary criticism? Thirty well known contributors reflect on these questions, including iterary theorists Marshall Gregory, James (...) Phelan, and Wayne Booth; philosophers Martha Nussbaum, Richard Hart, and Nina Rosenstand; and authors John Updike, Charles Johnson, Flannery O'Connor, and Bernard Malamud. Divided into four sections, with introductory matter and questions for discussion, this accessible anthology represents the most crucial work today exploring the interdisciplinary connections between literature, religion and philosophy. (shrink)

Contemporary tort theory is dominated by a debate between legal economists and corrective-justice theorists. Legal economists suppose that tortfeasors and tortious wrongs are false targets for cheapest cost-avoiders and avoidable future losses. Corrective-justice theorists argue powerfully that the economic account of tort as search for cheapest cost-avoiders with respect to future accidents does not capture the most fundamental fact about tort adjudication, namely, that the reason we hold defendants liable in tort is that they have wronged their victims and should (...) therefore repair the harm they have done. Deterring cheapest cost-avoiders from committing future harms no more justifies imposing liability in tort than deterring future crime justifies hanging the innocent. This is a powerful critique of the economic theory of tort, but it overshoots the mark. As an account of tort law, corrective justice puts the cart before the horse Tort is a law of wrongs, not just a law of redress for wrongs. Repairing harm wrongly done is the next best way of complying with an obligation not to do harm wrongly in the first place. Rights and remedies form a unity in which rights have priority. Corrective justice is thus an essential but subordinate aspect of tort. This paper develops this line of criticism of corrective-justice theory and offers an alternative account of tort that places primary norms of harm avoidance and respect for rights at its center. On this conception, tort isa law of wrongs, but its distinctiveness lies in the content and character of the wrongs with which it is concerned. At its core, tort is concerned with protecting essential conditions of individual agency. (shrink)

Pancreatitis is a complex, progressively destructive inflammatory disorder. Alcohol was long thought to be the primary causative agent, but genetic contributions have been of interest since the discovery that rare PRSS1, CFTR and SPINK1 variants were associated with pancreatitis risk. We now report two associations at genome-wide significance identified and replicated at PRSS1-PRSS2 and X-linked CLDN2 through a two-stage genome-wide study. The PRSS1 variant likely affects disease susceptibility by altering expression of the primary trypsinogen gene. The CLDN2 risk allele is (...) associated with atypical localization of claudin-2 in pancreatic acinar cells. The homozygous CLDN2 genotype confers the greatest risk, and its alleles interact with alcohol consumption to amplify risk. These results could partially explain the high frequency of alcohol-related pancreatitis in men. © 2012 Nature America, Inc. All rights reserved. (shrink)

Writing in the late 1990s about the tendency of encyclopedists to designate existentialism a finished project, Thomas W. Busch cautions that such hasty periodization risks distorting our understanding of the contemporary philosophical scene and of depriving ourselves of vital resources for critiquing contemporary forms of oppression, what Garbriel Marcel referred to as processes of dehumanization. We should recall that "existentialism made possible present forms of Continental philosophy, all of which assume the existentialist critique of dualism, essentialism, and totality in modern (...) philosophy," and we should acknowledge that "existentialism remains capable of haunting today's scene as an important and relevant critic." Offered in honor of Thomas W. Busch after his more than fifty years of work in philosophy, the essays in this volume attest to existentialism as a living project. The essays are written by scholars who championed existentialism in America and by scholars who now seek to extend existentialist insights into new territory, including into research in cognitive science. The essays range from studies of key figures and texts to explorations of urgent topics such as the nature of freedom and the possibility of what Busch calls "incorporation," a sense of communicative solidarity that respects difference and disagreement. (shrink)

From a traditional moral point of view, business practitioners often seem overly concerned about the behavior of their peers in deciding how they ought to act. We propose to account for this concern by introducing a mutual trust perspective, where moral obligations are grounded in a sense of trust that others will abide by the same rules. when grounds for trust are absent, the obligation is weakened. We illustrate this perspective by examining the widespread ambivalence with regard to deception about (...) one's settlement preferences in negotiation. On an abstract level, such deception generally seems undesirable, though in many individual cases it is condoned, even admired as shrewd bargaining. Because of the difficulty in verifying someone's settlement preferences, it is hard to establish a basis for trusting the revelations of the other party, especially in competitive negotiations with relative strangers. (shrink)

This article investigates teachings from diverse mystical traditions and the quantum physicist, David Bohm. After a brief background on the traditions, a dialogue follows their teachings regarding these questions: How is infinite truth described? How does the phenomenal world relate to infinite truth? How do humans experience the infinite within the phenomenal world? The metaphors from quantum physics proposed by David Bohm poetically intertwine topics of emptiness, innermost awareness, sparks and relationships, storehouses and the heart, roots and souls, resurrection and (...) the truth body, and perceiving truth. (shrink)

Flesh of My Flesh is a collection of articles by today's most respected scientists, philosophers, bioethicists, theologians, and law professors about whether we should allow human cloning. It includes historical pieces to provide background for the current debate. Religious, philosophical, and legal points of view are all represented.

Searching for God draws upon the traditional categories of systematic theology as it guides readers through the Catholic theological thought process involved in the search for God. At each step we examine the work of a past thinker from the time of the early church up to the early twentieth century, and a present thinker whose works are often required reading in theology courses. Not only do readers have the opportunity to critically evaluate several important theological works in the Catholic (...) tradition, they can also enter into dialogue with those works as they engage in their own search for God. Among the ten categories represented are: Bible: Hearing God--Past: Hugh of St. Victor, Noah's Ark (ca. 1130) Present: Sandra Schneiders, The Revelatory Text (1999) Christ II: Understanding God (Dogmatic Approach)--Past: Cyril of Alexandria, On the Unity of Christ (429) Present: Roger Haight, Jesus: Symbol of God (1999) Religions of the World: Listening for God Past: Jean Daniélou, The Salvation of the Nations (1946) Present: Raimon Panikkar, The Experience of God (2006) +. (shrink)

We use the path integral form of quantum electrodynamics to show that a causal classical limit to QED can be derived by functionally integrating over the photon coordinates, starting from an initial photon vacuum and ending in a final coherent radiation state driven by the anticipated classical charged particle trajectories. The resulting charged particle transition amplitude depends only on particle coordinates. When the \ limit is taken, only those particle paths that are not constrained by the final radiation state are (...) varied. These results demonstrate that the collapse from an infinity of charged particle paths, a path integral description, to causally interacting classical trajectories, a stationary-action description, is critically dependent on including final coherent state radiation and maintaining the distinction between particle paths that are free to vary and those trajectories that can be monitored by the final state radiation. (shrink)

Blair proposes that fluid intelligence, working memory, and executive function form a unitary construct: fluid cognition. Recently, our group has utilized a combined correlational–experimental cognitive neuroscience approach, which we argue is beneficial for investigating relationships among these individual differences in terms of neural mechanisms underlying them. Our data do not completely support Blair's strong position. (Published Online April 5 2006).

In the move from a teleological notion of history to one ruled by the logic of the symptom, Žižek is pushed to theorize the notion of the Act. Bringing together Marxism and psychoanalysis at the level of surplus, revolution and the end of analysis merge. What Žižek provides is a picture of change permeated with contingencies: a hysterical ‘acting out’ can become the Act proper; a violent outburst can become revolution. This can only be accomplished with the help of the (...) party-cum-analyst, which Zizek asserts serves to ensure that spontaneity becomes politicized. This paper serves as an attempt to trace the beginnings of the theoretical contours of Žižek’s development of the Act, and ends by opening towards the investigation of the importance of Pascal’s wager in Žižek’s theoretical corpus. (shrink)

While he develops three different aspects of Lacan's “Real,” Slavoj Žižek does so only partially, in the end leaving an inconsistent and contradictory account. Here these three versions of the Real are outlined and clarified by showing their relation to Marx's account of capitalist exchange and socialist politics. This leads to a discussion of two other aspects of the Real that appear in Žižek's work: the pre-Symbolic Real and the “Sinthome.” Where the former is simultaneously the fear of a unified (...) working class and the fantasy of a world of “total enjoyment” without conflict, the latter is discussed here in terms of political struggle that takes on not only the form of a means to an end but also that of an end in itself. (shrink)

As a way forward in assessing how the Old Testament wisdom tradition might speak to decisions in a modern medical context, in this paper, I propose exploring the iconographic function of the “tree of life” in the Old Testament, which is consistently associated with both wisdom as well as life and health, in order to tease out two-related issues that can help in providing a Christian theological framework for thinking about the problem of the medicalization of risk: first, how should (...) the natural and good human desire for health and long life be framed in terms of the pursuit of wisdom? And, second, how might a sapientially formed character approach risk and uncertainty in making medical decisions? The answers to these questions help establish a framework in which more specific questions related to the medicalization of risk can be assessed. As such, this paper is deliberately programmatic and perspectival rather than prescriptive. (shrink)

The ideas contained in Karl Popper's The Open Society and Its Enemies—one of the most important tracts in political philosophy in the twentieth century—are relevant to anyone seeking to understand the recent history of the East Asian economies. Even though Popper wrote his tract to provide an explanation for both the rise and objectionable nature of totalitarian regimes in Europe in the twentieth century, many of the arguments that he advanced in this European context also explain the social, political and (...) economic relationships that are seen in modern South Eastern Asian economies. The narrative of this book is driven by a research agenda that is inter-disciplinary in nature, since to make the link between the Popperian framework and East Asian socio-economic relationships the contributing authors needed to draw upon research fields as far apart as political philosophy and East-Asian studies. With one or two exceptions, however, nearly all of the contributing authors have a background in economics, and this background is reflected in the way that they have sought to tackle the research question. This book is, in short, an inter-disciplinary exercise undertaken from an economics perspective, and hence it may best be described as an exercise in political economy rather than pure analytical economics. The novelty of juxtaposing Popperian ideas with a discussion of social, political and economic development in South East Asia makes this narrative of interest to both political philosophers and specialists in South East Asian economies. The key insight drawn from the analysis is that although Karl Popper's The Open Society and Its Enemies was a product of a European time and place, it is also relevant to anyone seeking to understand the recent history of the East Asian economies. (shrink)

Traditionally, logic has been the dominant formal method within philosophy. Are logical methods still dominant today, or have the types of formal methods used in philosophy changed in recent times? To address this question, we coded a sample of philosophy papers from the late 2000s and from the late 2010s for the formal methods they used. The results indicate that the proportion of papers using logical methods remained more or less constant over that time period but the proportion of papers (...) using probabilistic methods was approximately three times higher in the late 2010s than it was in the late 2000s. Further analyses explored this change by looking more closely at specific methods, specific levels of technical engagement, and specific subdisciplines within philosophy. These analyses indicate that the increasing proportion of papers using probabilistic methods was pervasive, not confined to particular probabilistic methods, levels of sophistication, or subdisciplines. (shrink)

A young boy found one of Beck's best stereoscopes, but he did not understand its use. When he looked through the two eye-pieces at the two adjacent duplicates of each picture on each card he got a single flat picture, and he expected nothing more. Then the moment of revelation came. As he fumbled the focus onto a flat picture of Hamlet, the grave-diggers and Hamlet himself bulged out, the skull on Hamlet's palm looked like a museum piece, and the (...) grave yawned like a real pit. The stereoscopic world of the Beck instrument had been suddenly established in the boy's experience. (shrink)

When a rainbow spans the sky the eye may rest with simple rapture on the arch of colours, or the mind may interpret it as an interplay between raindrops and light. This perceptibly separates the aesthetic relish of the colours from the scientific understanding of the bow. Archbishop Temple distinguished the restfulness of art from the restlessness of science. This applies to the wider aesthetic which includes natural products, such as snow-scenes or daffodils or rainbows, with the pictures, statues, buildings, (...) poems, and other products of man-made art. The rainbow clearly separates the understanding sought by science from the immediate contemplative aesthetic satisfaction with the colours. (shrink)

The tomb of the ancient Pharaoh, Tut-ankh-Amen, was opened some years ago. Lord Carnarvon, who financed the investigations, died shortly after the opening. Lord Westbury fell to his death from the high window of a London flat on February 21, 1930. His son, the Hon. Richard Bethell, had been found dead in his room the previous November. He was secretary to Mr. Howard Carter, one discoverer of Tut-ankh-Amen’s tomb. Many persons who had been connected with the excavations had died previously—M. (...) Benedite, for example, died after participating in the research, and Mrs. Greely committed suicide after visiting the tomb. The Hon. Richard Bethell was the thirteenth person connected with Tut-ankh-Amen's tomb, directly or indirectly, to die, and his father, Lord Westbury, was the fourteenth. The death of Lord Carnarvon, a few weeks after the tomb was opened, stirred the notion that a curse had been placed on the mummy of the Pharaoh, or in his tomb, to menace violators. Succeeding deaths kept the notion alive, and the thirteenth death, of the Hon. Richard Bethell, wrung an opinion from Dr. Mardus, the eminent French Egyptologist. He was convinced that the ancient Egyptians could surround “their mummies with some dynamic force.” Such a force lurked in the tomb of Tut-ankh-Amen. Its nature was unknown, but it had manifested itself in the series of deaths. (shrink)